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Ger J M Pruijn Selected Research

Cartilage-hair hypoplasia

1/2022A novel experimental approach for the selective isolation and characterization of human RNase MRP.
1/2017Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation.
7/2011Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease.
3/2008Cartilage-hair hypoplasia-associated mutations in the RNase MRP P3 domain affect RNA folding and ribonucleoprotein assembly.
11/2007Cartilage hair hypoplasia mutations that lead to RMRP promoter inefficiency or RNA transcript instability.

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Ger J M Pruijn Research Topics

Disease

30Rheumatoid Arthritis
02/2022 - 08/2003
16Autoimmune Diseases (Autoimmune Disease)
01/2020 - 01/2005
8Polymyositis
01/2018 - 02/2004
8Myositis (Idiopathic Inflammatory Myopathies)
01/2018 - 01/2002
8Arthritis (Polyarthritis)
06/2017 - 01/2006
6Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2018 - 09/2002
6Inclusion Body Myositis
01/2018 - 03/2013
6Dermatomyositis (Dermatopolymyositis)
01/2018 - 07/2007
5Inflammation (Inflammations)
01/2022 - 06/2005
5Cartilage-hair hypoplasia
01/2022 - 11/2007
4Neoplasms (Cancer)
08/2020 - 01/2010
3Multiple Sclerosis
03/2014 - 06/2005
2Necrosis
01/2020 - 12/2011
2Relapsing-Remitting Multiple Sclerosis
06/2018 - 08/2015
2Neuromuscular Diseases (Neuromuscular Disease)
04/2016 - 11/2015
2Neoplasm Metastasis (Metastasis)
04/2014 - 03/2013
2Squamous Cell Carcinoma of Head and Neck
04/2014 - 03/2013
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2011 - 01/2010
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
09/2006 - 06/2005
2Mixed Connective Tissue Disease (MCTD)
07/2005 - 01/2005
2Systemic Scleroderma (Systemic Sclerosis)
10/2003 - 03/2003
1Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
01/2022
1Lymphoma (Lymphomas)
01/2022
1Facioscapulohumeral Muscular Dystrophy
01/2021
1Rupture
12/2020
1Infections
11/2020
1Cardiomyopathies (Cardiomyopathy)
10/2018
1Mitochondrial Diseases (Mitochondrial Disease)
10/2018
1Hypertrophy
01/2017
1Psoriatic Arthritis
12/2016
1Muscular Diseases (Myopathy)
12/2016
1Ankylosing Spondylitis
12/2016
1Chronic Disease (Chronic Diseases)
08/2015
1Experimental Arthritis
05/2014
1Periodontal Diseases (Periodontal Disease)
05/2014
1Periodontitis
05/2014
1Hypoxia (Hypoxemia)
04/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
03/2014
1Breast Neoplasms (Breast Cancer)
12/2013
1Starvation
06/2013
1Frailty
11/2012

Drug/Important Bio-Agent (IBA)

35AutoantibodiesIBA
02/2022 - 01/2002
25Proteins (Proteins, Gene)FDA Link
12/2018 - 03/2003
15Peptides (Polypeptides)IBA
01/2022 - 03/2003
11AntibodiesIBA
01/2021 - 08/2003
10Anti-Citrullinated Protein AntibodiesIBA
06/2017 - 01/2008
9AntigensIBA
01/2021 - 08/2003
8RNA (Ribonucleic Acid)IBA
01/2022 - 11/2007
7AutoantigensIBA
01/2011 - 10/2003
6EpitopesIBA
04/2016 - 01/2005
5Protein-Arginine DeiminasesIBA
06/2017 - 09/2006
4Biomarkers (Surrogate Marker)IBA
01/2020 - 12/2010
4EnzymesIBA
10/2018 - 01/2006
35'-Nucleotidase (5' Nucleotidase)IBA
01/2018 - 03/2013
3mitochondrial RNA-processing endoribonuclease (RNAse MRP)IBA
01/2017 - 03/2008
3Amino AcidsFDA Link
01/2017 - 05/2012
3Fibrinogen (Factor I)FDA Link
12/2016 - 01/2010
3Crystallins (Crystallin)IBA
04/2014 - 03/2013
3CitrullineIBA
05/2012 - 08/2003
2MicroRNAs (MicroRNA)IBA
08/2020 - 09/2011
2Nucleic AcidsIBA
01/2020 - 08/2015
2Cell-Free Nucleic AcidsIBA
06/2018 - 08/2015
2acetyl 4-aminosalicylic acidIBA
01/2018 - 06/2017
2Immunoglobulin G (IgG)IBA
06/2017 - 03/2016
2Messenger RNA (mRNA)IBA
04/2014 - 06/2013
2Acetylcysteine (Siran)FDA LinkGeneric
04/2014 - 06/2013
2Antigen-Antibody Complex (Immune Complex)IBA
01/2009 - 01/2008
2Glial Fibrillary Acidic ProteinIBA
09/2006 - 06/2005
2Myelin Basic ProteinIBA
09/2006 - 06/2005
2U1 Small Nuclear RibonucleoproteinIBA
07/2005 - 01/2005
2Small Nuclear Ribonucleoproteins (snRNP)IBA
01/2005 - 09/2002
1Polysaccharides (Glycans)IBA
02/2022
1Rituximab (Mabthera)FDA Link
01/2022
1DNA (Deoxyribonucleic Acid)IBA
01/2022
1Organosilicon CompoundsIBA
12/2020
1SiliconesIBA
12/2020
1Tuberculosis VaccinesIBA
11/2020
1ProdrugsIBA
12/2018
1Gln Transfer RNAIBA
10/2018
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2017
1HLA-DRB1 Chains (HLA DRB1)IBA
01/2017
1RNA Precursors (Precursor, mRNA)IBA
01/2017
1Long Noncoding RNAIBA
01/2017
1Protein Subunits (Protein Subunit)IBA
01/2017
1serum P-component (CIt)IBA
12/2016
1Collagen Type II (Type II Collagen)IBA
05/2014
1Interleukin-6 (Interleukin 6)IBA
05/2014
1Interleukin-17 (Interleukin 17)IBA
05/2014
1Reactive Oxygen Species (Oxygen Radicals)IBA
04/2014
1pimonidazoleIBA
04/2014
1Small Heat-Shock ProteinsIBA
04/2014
1Methionine (L-Methionine)FDA Link
06/2013
1AntioxidantsIBA
06/2013
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2013
1Differentiation AntigensIBA
01/2013
1ApolipoproteinsIBA
01/2013
1Arginine (L-Arginine)FDA Link
05/2012
1HLA Antigens (Human Leukocyte Antigens)IBA
02/2012

Therapy/Procedure

3Therapeutics
12/2013 - 01/2006
1Breast Implants (Breast Implant)
12/2020